1980s
| 1981 | Feb | Japan Lifeline Co., Ltd. established in Toshima-ku, Tokyo, Japan Released cardiac pacemaker Opened Sapporo, Osaka and Fukuoka sales offices |
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| 1987 | Sep | Opened Sendai and Hamamatsu sales offices |
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| 1989 | Mar | Released PTCA balloon catheter |
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| Jul | Opened Aomori and Nagoya sales offices | |
| Sep | Opened Hiroshima sales office |
1990s
| 1990 | Mar | Released prosthetic heart valve |
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| Sep | Opened Kagoshima sales office |
| 1991 | Jul | Opened Hokuriku sales office Released vascular graft |
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| 1992 | Jan | Opened logistics center (currently Haneda Logistics Center) |
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| Feb | Opened Urawa sales office | |
| Apr | Opened Tokyo (currently Tokyo sales officeⅠ) and Matsuyama sales offices | |
| Sep | Opened Yokohama and Okayama sales offices |
| 1993 | Oct | Opened Niigata sales office |
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| 1994 | Jan | Released PTCA guide wire |
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| Mar | Released PTCA guiding catheter | |
| Jun | Opened Kitakyushu sales office | |
| Oct | Opened Akita and Takamatsu sales offices Released pump-oxygenator |
| 1995 | Nov | Released oxygenator and electrophysiology catheter |
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| 1996 | Nov | Opened Koriyama sales office |
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| 1997 | Oct | Opened Kyoto sales office |
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| Dec | Registered over-the-counter stock with the Japan Securities Dealers Association, initial public offering |
| 1998 | Feb | Released PTCA stent |
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| 1999 | Aug | Established Research center (currently 1st R&D Division and 2nd R&D Division) |
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2000s
| 2000 | Oct | Established Ukima factory (manufacturing facility) |
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| 2001 | Apr | Opened Matsumoto sales office Released PTCA guide wires as an in-house product |
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| Aug | Released ICD (implantable cardioverter defibrillator) | |
| Oct | Opened Nagasaki sales office |
| 2003 | Apr | Opened Chiba sales office Released ablation catheter as an in-house product |
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| 2004 | Apr | Released electrophysiology catheter as an in-house product Opened Yonago sales office |
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| 2005 | Aug | Released atrial septal defect closing device |
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| Nov | Opened Okinawa regional office (currently sales office) |
| 2006 | Apr | Acquired ISO13485:2003 certification (For the Quality Assurance Division, Ichihara Factory, Toda Factory,Oyama Factory, Haneda Logistics Center,and Kansai Logistics Center) Opened Kumamoto regional office (currently sales office) |
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| Dec | Released CRT-D (cardiac resynchronization therapy defibrillators) |
| 2007 | Jun | Entered into exclusive sales agreement for Sorin Group CRM (MicroPort CRM)(cardiac rhythm management) products |
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| Jul | Opened Tennoz Accademia (Education center) | |
| Sep | Merged with Sorin Group Japan Co., Ltd. through absorption-type merger Opened Morioka regional office |
| 2008 | Jan | Relocated head office to shinagawa-ku, Tokyo |
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| 2009 | Feb | Subsidized JUNKEN MEDICAL Co., Ltd.(formerly Ube Junken Co.,Ltd.) |
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| Apr | Released vascular grafts manufactured by JUNKEN MEDICAL Co., Ltd. |
2010s
| 2010 | May | Opened Ibaraki regional office (currently sales office) |
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| Oct | Opened Kobe sales office | |
| Dec | Estbablished Ichihara factory by JUNKEN MEDICAL Co., Ltd. |
| 2011 | Oct | Opened Tama sales office |
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| 2012 | Jan | Established Toda factory |
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| Apr | Opened Gunma and Oita regional offices (currently sales offices) | |
| Oct | Released internal atrial cardioversion catheter as an in-house product | |
| Nov | Released biological heart valve | |
| Dec | Established HEART BRAINS INC. |
| 2013 | May | Released thoracic stent graft Released radio-frequency transseptal needle |
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| 2014 | Apr | Released PTCA balloon catheter as an in-house product |
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| Jul | Released frozen elephant trunk manufactured by JUNKEN MEDICAL | |
| Oct | Established Oyama Factory |
| 2015 | Apr | Released esophageal temperature monitoring catheter as an in-house product |
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| Dec | Opened Numazu regional office |
| 2016 | Jan | Released abdominal stent graft Merged with HEART BRAINS INC. through absorption-type merger |
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| May | Changed exchange market from the JASDAQ (Standard) market to the First Section of the Tokyo Stock Exchange | |
| Jul | Opened Hakodate and Mie (currently sales office) regional offices |
| 2017 | Apr | Merged with JUNKEN MEDICAL Co., Ltd. through absorption-type merger Opened Tokyo sales office Ⅱ and Fukui (currently sales office), Nara (currently sales office), Himeji (currently sales office), Yamaguchi and Miyazaki regional offices |
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| May | Opened Asahikawa and Kushiro regional offices | |
| Jun | Released colonic stent as an in-house product | |
| Jul | Established JLL Malaysia Sdn. Bhd. (currently consolidated) | |
| Oct | Opened Utsunomiya and Shizuoka regional offices (currently sales offices) |
| 2018 | Mar | Released drug-eluting stent |
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| Apr | Opened Kochi regional office | |
| Jul | Opened Kansai Logistics Center Released endoscopic laser ablation catheter |
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| Nov | Entered into exclusive sales agreement for Boston Scientific corporation for CRM (cardiac rhythm management) products |
| 2019 | Apr | Released S-ICD (subcutaneous implantable cardioverter defibrillator) |
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| Nov | Established JLL Korea Co.,Ltd. (non-consolidated) | |
| Dec | Released radiofrequency ablation system for the treatment of liver cancer as an in-house product |
2020s
| 2020 | Jun | Opened Yamagata and Yamanashi regional offices Estbablished Malaysia factory by JLL Malaysia Sdn. Bhd. |
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| 2021 | Dec | Released intravascular embolic coil |
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| 2022 | Feb | Released implantable treatment device for obstructive sleep apnea (OSA) |
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| Apr | Changed exchange market from the First Section to Prime of the Tokyo Stock Exchange | |
| Aug | Entered into exclusive sales agreement for Wallaby Medical (HK) Limited for Neurovascular Products | |
| Oct | Released Patch-Type ECG Recorder |
| 2023 | May | Released thrombus aspiration catheter Acquired MDSAP (Medical Device Single Audit Program) |
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| Oct | Released vascular closure device for femoral veins Entered into exclusive distribution agreement for Meril Life Sciences Pvt. Ltd. for transcatheter heart valve |
| 2024 | Sep | Released stent retriever |
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| 2025 | Mar | Entered into an exclusive distribution agreement for Philips Japan, Ltd. for Lead management products |
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